Peer-Reviewed Publication

Hitting Moving Targets in Cancer Treatment.

Fagerstrom JM, Bry VN, Colbert CM and Windsor CFront. Young Minds. 12:1349460. doi: 10.3389/frym.2024.1349460 23, 4 (2024). In this article, we will explore the way radiation can be used to treat cancer. Radiation for cancer therapy consists of high-energy particles or light that can damage living cells, including cancer cells. Radiation beams can be generated using a…

AAPM medical physics practice guideline 13.a: HDR brachytherapy, part A

Susan L. Richardson, Ivan M. Buzurovic, Gil’ad N. Cohen, Wesley S. Culberson, Claire Dempsey, Bruce Libby, Christopher S. Melhus, Robin A. Miller, Daniel J. Scanderbeg, Samantha J. Simiele Journal of Applied Clinical Medical Physics (2023). The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the…

AAPM Medical physics practice guideline 15.A: Peer review in clinical physics

Per H. Halvorsen, Alan H. Baydush, Courtney R. Buckey, Navneeth Hariharan, Mary A. Keenan, Jeffrey P. Limmer, Kate E. Lofton, Robin A. Miller, Jeffrey M. Moirano, Joseph Och, Douglas E. Pfeiffer Journal of Applied Clinical Medical Physics (2023). The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are…

Overview of medical physics education and research programs in a non-academic environment

Jessica M. Fagerstrom,1 Thomas A. D. Brown,2 Darryl G. L. Kaurin,3 Saikanth Mahendra,3 M. Miron Zaini31University of Washington, Seattle, WA; 2Maine Medical Center, Portland, ME; 3Northwest Medical Physics Center, Lynnwood, WA Journal of Applied Clinical Medical Physics (2023). Northwest Medical Physics Center (NMPC) is a nonprofit organization that provides clinical physics support to over 35 radiation therapy facilities concentrated in the…

Equity, diversity, and inclusion topics at a medical physics residency journal club

Jessica M. Fagerstrom,1 Cheyann Windsor,2 Daniel Zaks21University of Washington, Seattle, WA; 2Northwest Medical Physics Center, Lynnwood, WA Journal of Applied Clinical Medical Physics (2023). A journal club program was initiated in a clinically focused, geographically distributed medical physics therapy residency program. This program currently supports two residents at different clinical sites, who regularly present at the new journal…

Therapeutic radiation beam output and energy variation across clinics, technologies, and time

Mehran Miron Zaini,1 Jessica M. Fagerstrom,1 Edward I. Marshall,1 Kathryn M. Hedrick,1 Daniel Zaks,1 Hung Tran,1 Trevor M. Fitzgerald11Northwest Medical Physics Center, Lynnwood, WA  Journal of Applied Clinical Medical Physics (2023). Over the past several decades, a medical physics service group covering 35 clinical sites has provided routine monthly output and energy quality assurance for over 75 linear accelerators. Based on…

Determination of commissioning criteria for multileaf-collimator, stereotactic radiosurgery treatments on Varian TrueBeam and Edge machines using a novel anthropomorphic phantom

Thomas A. D. Brown,1 Jessica M. Fagerstrom,1 Caleb Beck,1 Connor Holloway,1 Krista Burton,1 Darryl G. L. Kaurin,1 Saikanth Mahendra,1 Marcus Luckstead,1 Kayla Kielar,2 James Kerns21Northwest Medical Physics Center, Lynnwood, WA; 2Varian Medical Systems, Palo Alto, CA Journal of Applied Clinical Medical Physics, 23, 4 (2022). An anthropomorphic phantom has been developed by Varian Medical Systems for commissioning multileaf-collimator (MLC), stereotactic radiosurgery (SRS) treatments on Varian TrueBeam and…

Commissioning a multileaf collimator virtual cone for the stereotactic radiosurgery of trigeminal neuralgia

Thomas A. D. Brown,1 Rex G. Ayers,1 Richard A. Popple21Northwest Medical Physics Center, Lynnwood, WA; 2University of Alabama at Birmingham, Birmingham, AL Journal of Applied Clinical Medical Physics, 23, 4 (2022). A multileaf collimator (MLC), virtual-cone treatment technique has been commissioned for trigeminal neuralgia (TGN) at Tri-Cities Cancer Center (TCCC). This novel technique was initially developed at the University of…

Resilience: Learning and healing during COVID-19

Jessica M. Fagerstrom1 1Northwest Medical Physics Center, Lynnwood, WA  Practical Radiation Oncology, 11, 6 (2021). A community education art project was undertaken as a partnership between Northwest Medical Physics Center and student artists at Franklin High School in Seattle, Washington, to celebrate community resilience in the face of challenges during the coronavirus disease 2019 (COVID-19) pandemic. Franklin…

Fury Road: Medical physics education using film

Jessica M. Fagerstrom,1 Edward I. Marshall,1 Matthew J. Nyflot,2 Jessica R. Miller3 1Northwest Medical Physics Center, Lynnwood, WA; 2University of Washington School of Medicine, Seattle, WA; 3University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI The Physics Teacher, 59, 3 (2021). As part of a public education outreach effort, an introduction to the health effects of ionizing radiation and the…

A Gottingen minipig model of radiation-induced coagulopathy

Karla D. Thrall,1 Saikanth Mahendra,2 Keven Jackson1 1Altasciences Preclinical Seattle, Everett, WA; 2Northwest Medical Physics Center, Lynnwood, WA International Journal of Radiation Biology, 96, 12 (2020). Purpose:  Total body irradiation of the Gottingen minipig results in a characteristic hematopoietic response, including anemia, neutropenia, lymphocytopenia, and thrombocytopenia. Currently, there are no well-characterized large or small animal models for radiation-induced thrombocytopenia. The study…

Simple phantom fabrication for MRI‐based HDR brachytherapy applicator commissioning

Jessica M. Fagerstrom,1,2 Sukhjit Kaur1 1Northwest Medical Physics Center, Lynnwood, WA; 2Kaiser Permanente, Seattle, WA Journal of Applied Clinical Medical Physics, 21, 11 (2020). A new high dose rate (HDR) brachytherapy program was initiated in a community hospital setting, with the goal of using magnetic resonance (MR) images with the implant in place during the planning process. Physics acceptance…

Computed tomography, sinograms, and image reconstruction in the classroom

Jessica M. Fagerstrom11Northwest Medical Physics Center, Lynnwood, WA Physics Education, 55, 3 (2020). As part of an undergraduate introductory survey course on medical physics, x-ray computed tomography (CT) was used to illustrate fundamental principles and mathematics in imaging science. A qualitative description of sinograms was presented to students through a hands-on activity involving simple classroom materials, then the…

Introducing health and medical physics to young learners in preschool to fifth grade

Jessica M. Fagerstrom11Northwest Medical Physics Center, Lynnwood, WA Health Physics, 118, 1 (2020). A hands-on learning activity was developed to introduce young learners to concepts and careers in health and medical physics. Inexpensive materials were used to create a work station with learning tools that were designed to be approachable and accessible for this audience. Visitors to a…

A comparative dose-response relationship between sexes for mortality and morbidity of radiation-induced lung injury in the rhesus macaque

Karla D. Thrall,1 S. Mahendra,2 M. K. Jackson,1 William Jackson III,3 Ann M. Farese,4 Thomas J. MacVittie4 1SNBL USA, Ltd, Everett, WA; 2Northwest Medical Physics Center, Lynnwood, WA; 3Statistician, Rockville, MD; 4University of Maryland, School of Medicine, Department of Radiation Oncology, Baltimore, MD Health Physics, 116, 3 (2019). Radiation-induced lung injury is a characteristic, dose- and time-dependent sequela of potentially lethal, delayed effects of acute…

A hands‐on introduction to medical physics and radiation therapy for middle school students

Jessica M. Fagerstrom,1 Wendy Gao,2 Gene E. Robertson1 1Northwest Medical Physics Center, Lynnwood, WA; 2Tacoma Valley Radiation Oncology Centers, Puyallup, WA Journal of Applied Clinical Medical Physics, 20, 4 (2019). Lesson plans were developed to present concepts of medical physics and radiation therapy to a middle school audience. These workshop learning units relied on hands‐on participation and collaboration within student…

Dosimetric characterization of a rigid, surface-contour-specific thermoplastic bolus material

Jessica M. Fagerstrom1,2 1Northwest Medical Physics Center, Lynnwood, WA; 2Kaiser Permanente, Seattle, WA Medical Dosimetry, 44, 4 (2019). A dosimetric analysis of a commercially available thermoplastic sheet bolus, Klarity EZ BolusTM, was completed. Attenuation characteristics were evaluated using different configurations of a rectilinear water-mimicking plastic phantom irradiated by a high-energy linear accelerator using three photon energies, five electron…

Redefining and reinvigorating the role of physics in clinical medicine: A Report from the AAPM Medical Physics 3.0 Ad Hoc Committee

Ehsan Samei,1 Todd Pawlicki,2 Daniel Bourland,3 Erika Chin,4 Shiva Das,5 Mary Fox,6 D. Jay Freedman,7 Nicholas Hangiandreou,8 David Jordan,9 Melissa Martin,10 Robin Miller,11 William Pavlicek,12 Daniel Pavord,13 Lisa Schober,14 Bruce Thomadsen,15 Brendan Whelan16 1Duke University, Durham, NC; 2University of California, San Diego, CA; 3Wake Forest University, Winston-Salem, NC; 4British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC, Canada; 5University of North Carolina, Chapel Hill, NC; 6Minneapolis Radiation Oncology, Minneapolis, MN; 7Riverside Cancer Care Center, Newport News,…

Standardizing nomenclatures in radiation oncology

Charles S. Mayo (Chair),1 Jean M. Moran (Vice Chair),1 Walter Bosch,2 Ying Xiao,3 Todd McNutt,4 Richard Popple,5 Jeff Michalski,2 Mary Feng,6 Lawrence B. Marks,7 Clifton D. Fuller,8 Ellen Yorke,9 Jatinder Palta,10 Peter E. Gabriel,3 Andrea Molineu,8 Martha M. Matuszak,1 Elizabeth Covington,11 Kathryn Masi,12 Susan L. Richardson,13 Timothy Ritter,14 Tomasz Morgas,15 Stella Flampouri,16 Lakshmi Santanam,2 Joseph A. Moore,4 Thomas G. Purdie,17 Robert Miller,18 Coen Hurkmans,19 Judy Adams,20 Qing-Rong Jackie Wu,21 Colleen J. Fox,22 Ramon Alfredo Siochi,23 Norman L. Brown,24 Wilko Verbakel,25 Yves Archambault,15 Steven J. Chmura,26 Don G. Eagle,27 Thomas J….

Prototype modulated orthovoltage stereotactic radiosurgery cones

Jessica M. Fagerstrom,1 Larry A. DeWerd,2 Benjamin Palmer,2 Wesley S. Culberson21Northwest Medical Physics Center, Lynnwood, WA; 2Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI Radiation Measurements, 119, 33 (2018). This work sought create a set of prototype modulated orthovoltage stereotactic radiosurgery (SRS) cones, and to perform a dosimetric characterization of the prototypes. Four radiosurgical…

Experimental investigation of GafChromic® EBT3 intrinsic energy dependence with kilovoltage x-rays, 137Cs, and 60Co

Cliff G. Hammer,1 Benjamin Saul Rosen,2 Jessica M. Fagerstrom,3 Wesley S. Culberson,1 Larry A. DeWerd11Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI; 2Department of Radiation Oncology, University of Michigan, Ann Arbor, MI; 3Northwest Medical Physics Center, Lynnwood, WA Medical Physics, 45, 1 (2018). Purpose: To determine experimentally the intrinsic energy response, kbq, of EBT3 GafChromic radiochromic film with…

Proposed changes to the American Association of Physicists in Medicine governance

Todd Pawlicki,1 Rex G. Ayers,2 Kristy K. Brock,3 Jessica B. Clements,4 Bruce H. Curran,5 James T. Dobbins,6 Ehsan Samei,6 Eva Adams,7 Melissa Carol Martin,8 Lisa Schober91University of California, San Diego, CA; 2Northwest Medical Physics Center, Lynnwood, WA; 3University of Texas, MD Anderson Cancer Center, Houston, TX; 4Kaiser Permanente, Los Angeles, CA; 5Virginia Commonwealth University Medical Center, Richmond, VA; 6Duke University, Durham, NC; 7TG-281; 8Therapy Physics, Inc., Signal Hill, CA; 9AAPM, Columbia, MD…

AAPM Medical Physics Practice Guideline 8.a.: Linear accelerator performance tests

Koren Smith,1 Peter Balter,2 John Duhon,3 Gerald A. White Jr.,4 David L. Vassy Jr.,5 Robin A. Miller,6 Christopher F. Serago,7 Lynne A. Fairobent81Mary Bird Perkins Cancer Center, Baton Rouge, LA; 2MD Anderson Cancer Center, Houston, TX; 3e+ OncoLogics, Lafayette, LA; 4Colorado Associates in Medical Physics, Colorado Springs, CO; 5Spartanurg Regional Healthcare System, Spartanburg, SC; 6Northwest Medical Physics Center, Lynnwood, WA; 7Mayo Clinic, Jacksonville, FL; 8AAPM Headquarters Staff, Alexandria, VA…

“Brachytherapy Physics” in Comprehensive Biomedical Physics

B. Thomadsen,1 R. Miller21University of Wisconsin-Madison, Madison, WI; 2Northwest Medical Physics Center, Lynnwood, WA Book chapter. Anders Brahme, editor-in-chief, Vol 9, Amsterdam: Elsevier, 315-381 (2014). Brachytherapy is the treatment of disease using small radioactive sources placed in or near the tissues to be treated.    This chapter explores some of the most common sources used for brachytherapy as well…

VMAT testing for an Elekta accelerator

Darryl G.L. Kaurin,1,2 Larry E. Sweeney,1,2 Edward I. Marshall,1,2 Saikanth Mahendra1,21Northwest Medical Physics Center, Lynnwood, WA; 2Seattle Cancer Care Alliance, Radiation Oncology, Seattle, WA Journal of Applied Clinical Medical Physics, 13, 2 (2012). Volumetric-modulated arc therapy (VMAT) has been shown to be able to deliver plans equivalent to intensity-modulated radiation therapy (IMRT) in a fraction of the treatment time. This improvement…